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Visualizing the Bohr effect in hemoglobin: neutron structure of equine cyanomethemoglobin in the R state and comparison with human deoxyhemoglobin in the T state

Neutron crystallography provides direct visual evidence of the atomic positions of deuterium-exchanged H atoms, enabling the accurate determination of the protonation/deuteration state of hydrated biomolecules. Comparison of two neutron structures of hemoglobins, human deoxyhemoglobin (T state) and...

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Detalles Bibliográficos
Autores principales: Dajnowicz, Steven, Seaver, Sean, Hanson, B. Leif, Fisher, S. Zoë, Langan, Paul, Kovalevsky, Andrey Y., Mueser, Timothy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4932920/
https://www.ncbi.nlm.nih.gov/pubmed/27377386
http://dx.doi.org/10.1107/S2059798316009049