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Chronic hypoxia down‐regulates tight junction protein ZO‐2 expression in children with cyanotic congenital heart defect

AIMS: Tight junction protein zonula occludens protein 2 (ZO‐2) is a member of the membrane‐associated guanylate kinases protein family known to be expressed at tight junctions of epithelial and endothelial cells and at adherens junctions (AJs) in cardiomyocytes. Little is known about ZO‐2 expression...

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Detalles Bibliográficos
Autores principales: Jenkins, Emma L., Caputo, Massimo, Angelini, Gianni D., Ghorbel, Mohamed T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933037/
https://www.ncbi.nlm.nih.gov/pubmed/27398226
http://dx.doi.org/10.1002/ehf2.12081