γ-Aminobutyric Acid Type A (GABA(A)) Receptor Subunits Play a Direct Structural Role in Synaptic Contact Formation via Their N-terminal Extracellular Domains

The establishment of cell-cell contacts between presynaptic GABAergic neurons and their postsynaptic targets initiates the process of GABAergic synapse formation. GABA(A) receptors (GABA(A)Rs), the main postsynaptic receptors for GABA, have been recently demonstrated to act as synaptogenic proteins...

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Detalles Bibliográficos
Autores principales: Brown, Laura E., Nicholson, Martin W., Arama, Jessica E., Mercer, Audrey, Thomson, Alex M., Jovanovic, Jasmina N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933154/
https://www.ncbi.nlm.nih.gov/pubmed/27129275
http://dx.doi.org/10.1074/jbc.M116.714790

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933154/
https://www.ncbi.nlm.nih.gov/pubmed/27129275
http://dx.doi.org/10.1074/jbc.M116.714790

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