Fracture and Growth Are Competing Forces Determining the Fate of Conformers in Tau Fibril Populations

Tau fibrils are pathological aggregates that can transfer between neurons and then recruit soluble Tau monomers by template-assisted conversion. The propagation of different fibril polymorphs is thought to be a contributing factor to phenotypic diversity in Alzheimer disease and other Tauopathies. W...

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Detalles Bibliográficos
Autores principales: Meyer, Virginia, Holden, Michael R., Weismiller, Hilary A., Eaton, Gareth R., Eaton, Sandra S., Margittai, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933275/
https://www.ncbi.nlm.nih.gov/pubmed/27080260
http://dx.doi.org/10.1074/jbc.M116.715557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933275/
https://www.ncbi.nlm.nih.gov/pubmed/27080260
http://dx.doi.org/10.1074/jbc.M116.715557

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