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Prolonged Treatment with Propofol Transiently Impairs Proliferation but Not Survival of Rat Neural Progenitor Cells In Vitro

Neurocognitive dysfunction is common in survivors of intensive care. Prolonged sedation has been implicated but the mechanisms are unclear. Neurogenesis continues into adulthood and is implicated in learning. The neural progenitor cells (NPC) that drive neurogenesis have receptors for the major clas...

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Detalles Bibliográficos
Autores principales: Palanisamy, Arvind, Friese, Matthew B., Cotran, Emily, Moller, Ludde, Boyd, Justin D., Crosby, Gregory, Culley, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933334/
https://www.ncbi.nlm.nih.gov/pubmed/27379684
http://dx.doi.org/10.1371/journal.pone.0158058