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Prolonged Treatment with Propofol Transiently Impairs Proliferation but Not Survival of Rat Neural Progenitor Cells In Vitro
Neurocognitive dysfunction is common in survivors of intensive care. Prolonged sedation has been implicated but the mechanisms are unclear. Neurogenesis continues into adulthood and is implicated in learning. The neural progenitor cells (NPC) that drive neurogenesis have receptors for the major clas...
Autores principales: | Palanisamy, Arvind, Friese, Matthew B., Cotran, Emily, Moller, Ludde, Boyd, Justin D., Crosby, Gregory, Culley, Deborah J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933334/ https://www.ncbi.nlm.nih.gov/pubmed/27379684 http://dx.doi.org/10.1371/journal.pone.0158058 |
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