Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D(2) and D(3) Receptors

Many G protein-coupled receptors have been shown to be sensitive to the presence of sodium ions (Na(+)). Using radioligand competition binding assays, we have examined and compared the effects of sodium ions on the binding affinities of a number of structurally diverse ligands at human dopamine D(2)...

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Detalles Bibliográficos
Autores principales: Newton, Claire L., Wood, Martyn D., Strange, Philip G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933336/
https://www.ncbi.nlm.nih.gov/pubmed/27379794
http://dx.doi.org/10.1371/journal.pone.0158808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933336/
https://www.ncbi.nlm.nih.gov/pubmed/27379794
http://dx.doi.org/10.1371/journal.pone.0158808

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