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Examining the Effects of Sodium Ions on the Binding of Antagonists to Dopamine D(2) and D(3) Receptors
Many G protein-coupled receptors have been shown to be sensitive to the presence of sodium ions (Na(+)). Using radioligand competition binding assays, we have examined and compared the effects of sodium ions on the binding affinities of a number of structurally diverse ligands at human dopamine D(2)...
Autores principales: | Newton, Claire L., Wood, Martyn D., Strange, Philip G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933336/ https://www.ncbi.nlm.nih.gov/pubmed/27379794 http://dx.doi.org/10.1371/journal.pone.0158808 |
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