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Transforming Growth Factor-β1 T869C Gene Polymorphism Is Associated with Acquired Sick Sinus Syndrome via Linking a Higher Serum Protein Level

BACKGROUND: Familial sick sinus syndrome is associated with gene mutations and dysfunction of ion channels. In contrast, degenerative fibrosis of the sinus node tissue plays an important role in the pathogenesis of acquired sick sinus syndrome. There is a close relationship between transforming grow...

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Detalles Bibliográficos
Autores principales: Chen, Jan-Yow, Liu, Jiung-Hsiun, Wu, Hong-Dar Isaac, Lin, Kuo-Hung, Chang, Kuan-Cheng, Liou, Ying-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933337/
https://www.ncbi.nlm.nih.gov/pubmed/27380173
http://dx.doi.org/10.1371/journal.pone.0158676