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Conformational Stability of the NH(2)-Terminal Propeptide of the Precursor of Pulmonary Surfactant Protein SP-B

Assembly of pulmonary surfactant lipid-protein complexes depends on conformational changes coupled with proteolytic maturation of proSP-B, the precursor of pulmonary surfactant protein B (SP-B), along the surfactant biogenesis pathway in pneumocytes. Conformational destabilization of the N-terminal...

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Detalles Bibliográficos
Autores principales: Bañares-Hidalgo, Ángeles, Pérez-Gil, Jesús, Estrada, Pilar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933373/
https://www.ncbi.nlm.nih.gov/pubmed/27380171
http://dx.doi.org/10.1371/journal.pone.0158430