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Conformational Stability of the NH(2)-Terminal Propeptide of the Precursor of Pulmonary Surfactant Protein SP-B
Assembly of pulmonary surfactant lipid-protein complexes depends on conformational changes coupled with proteolytic maturation of proSP-B, the precursor of pulmonary surfactant protein B (SP-B), along the surfactant biogenesis pathway in pneumocytes. Conformational destabilization of the N-terminal...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933373/ https://www.ncbi.nlm.nih.gov/pubmed/27380171 http://dx.doi.org/10.1371/journal.pone.0158430 |