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Extracellular Regulation of Bone Morphogenetic Protein Activity by the Microfibril Component Fibrillin-1

Since the discovery of bone morphogenetic proteins (BMPs) as pluripotent cytokines extractable from bone matrix, it has been speculated how targeting of BMPs to the extracellular matrix (ECM) modulates their bioavailability. Understanding these processes is crucial for elucidating pathomechanisms of...

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Detalles Bibliográficos
Autores principales: Wohl, Alexander P., Troilo, Helen, Collins, Richard F., Baldock, Clair, Sengle, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933460/
https://www.ncbi.nlm.nih.gov/pubmed/27059954
http://dx.doi.org/10.1074/jbc.M115.704734