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MicroRNA-23a downregulates the expression of interferon regulatory factor-1 in hepatocellular carcinoma cells

Interferon regulatory factor-1 (IRF-1) is a tumor-suppressor gene induced by interferon-γ (IFNγ) and plays an important role in the cell death of hepatocellular carcinoma (HCC). HCC tumors evade death in part by downregulating IRF-1 expression, yet the molecular mechanisms accounting for IRF-1 suppr...

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Detalles Bibliográficos
Autores principales: Yan, Yihe, Liang, Zhihai, Du, Qiang, Yang, Muqing, Geller, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933546/
https://www.ncbi.nlm.nih.gov/pubmed/27279136
http://dx.doi.org/10.3892/or.2016.4864