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MicroRNA-23a downregulates the expression of interferon regulatory factor-1 in hepatocellular carcinoma cells
Interferon regulatory factor-1 (IRF-1) is a tumor-suppressor gene induced by interferon-γ (IFNγ) and plays an important role in the cell death of hepatocellular carcinoma (HCC). HCC tumors evade death in part by downregulating IRF-1 expression, yet the molecular mechanisms accounting for IRF-1 suppr...
Autores principales: | Yan, Yihe, Liang, Zhihai, Du, Qiang, Yang, Muqing, Geller, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933546/ https://www.ncbi.nlm.nih.gov/pubmed/27279136 http://dx.doi.org/10.3892/or.2016.4864 |
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