Targeting Transforming Growth Factor-Beta1 (TGF-β1) Inhibits Tumorigenesis of Anaplastic Thyroid Carcinoma Cells Through ERK1/2-NF-κB-PUMA Signaling

BACKGROUND: The transforming growth factor-beta (TGF-β) signaling pathway plays a critical role in promoting tumor growth. TGF-β1was found to be overexpressed in anaplastic thyroid cancer (ATC). We therefore tested our hypothesis that targeting TGF-β1 inhibits tumorigenesis of ATC cells. MATERIAL/ME...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Qiang, Liu, Shan, Dong, Anbing, Mi, Xiufang, Hao, Fengyun, Zhang, Kejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2016
Materias:
Lab/In Vitro Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933554/
https://www.ncbi.nlm.nih.gov/pubmed/27356491
http://dx.doi.org/10.12659/MSM.898702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933554/
https://www.ncbi.nlm.nih.gov/pubmed/27356491
http://dx.doi.org/10.12659/MSM.898702

Ejemplares similares