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Regulation of tumorigenesis in oral epithelial cells by defined reprogramming factors Oct4 and Sox2

Oct4 and Sox2 are pluripotent stem cell factors but the interplay between them in tumorigenesis is unclear. The aim of the present study was to investigate the roles of Oct4 and Sox2 in the reprogramming of oral cancer stem cells. One or both Oct4 and Sox2 were overexpressed in immortalized oral epi...

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Detalles Bibliográficos
Autores principales: Cai, Jinghua, He, Baoxia, Li, Xinming, Sun, Minglei, Lam, Alfred King-Yin, Qiao, Bin, Qiu, Weiliu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933556/
https://www.ncbi.nlm.nih.gov/pubmed/27279579
http://dx.doi.org/10.3892/or.2016.4851