A CD74-DEPENDENT MHC CLASS I ENDOLYSOSOMAL CROSS-PRESENTATION PATHWAY

Immune responses are initiated and primed by dendritic cells (DCs) that cross-present exogenous antigen. The CD74 (invariant chain) chaperone protein is thought to exclusively promote DC priming in the context of MHC class II. However, we demonstrate herein a CD74-dependent MHC class I cross-present...

Descripción completa

Detalles Bibliográficos
Autores principales: Basha, Genc, Omilusik, Kyla, Chavez-Steenbock, Ana, Reinicke, Anna T., Lack, Nathan, Choi, Kyung Bok, Jefferies, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933585/
https://www.ncbi.nlm.nih.gov/pubmed/22306692
http://dx.doi.org/10.1038/ni.2225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933585/
https://www.ncbi.nlm.nih.gov/pubmed/22306692
http://dx.doi.org/10.1038/ni.2225

Ejemplares similares