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A CD74-DEPENDENT MHC CLASS I ENDOLYSOSOMAL CROSS-PRESENTATION PATHWAY

Immune responses are initiated and primed by dendritic cells (DCs) that cross-present exogenous antigen. The CD74 (invariant chain) chaperone protein is thought to exclusively promote DC priming in the context of MHC class II. However, we demonstrate herein a CD74-dependent MHC class I cross-present...

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Detalles Bibliográficos
Autores principales:	Basha, Genc, Omilusik, Kyla, Chavez-Steenbock, Ana, Reinicke, Anna T., Lack, Nathan, Choi, Kyung Bok, Jefferies, Wilfred A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933585/ https://www.ncbi.nlm.nih.gov/pubmed/22306692 http://dx.doi.org/10.1038/ni.2225

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