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Age‐dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK‐AGE study

Aging is associated with alterations in the content and patterns of DNA methylation virtually throughout the entire human lifespan. Reasons for these variations are not well understood. However, several lines of evidence suggest that the epigenetic instability in aging may be traced back to the alte...

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Detalles Bibliográficos
Autores principales: Ciccarone, Fabio, Malavolta, Marco, Calabrese, Roberta, Guastafierro, Tiziana, Bacalini, Maria Giulia, Reale, Anna, Franceschi, Claudio, Capri, Miriam, Hervonen, Antti, Hurme, Mikko, Grubeck‐Loebenstein, Beatrix, Koller, Bernhard, Bernhardt, Jürgen, Schӧn, Christiane, Slagboom, P. Eline, Toussaint, Olivier, Sikora, Ewa, Gonos, Efstathios S., Breusing, Nicolle, Grune, Tilman, Jansen, Eugène, Dollé, Martijn, Moreno‐Villanueva, María, Sindlinger, Thilo, Bürkle, Alexander, Zampieri, Michele, Caiafa, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933658/
https://www.ncbi.nlm.nih.gov/pubmed/27169697
http://dx.doi.org/10.1111/acel.12485