A chromatin modifier integrates insulin/IGF‐1 signalling and dietary restriction to regulate longevity

Insulin/IGF‐1‐like signalling (IIS) and dietary restriction (DR) are the two major modulatory pathways controlling longevity across species. Here, we show that both pathways license a common chromatin modifier, ZFP‐1/AF10. The downstream transcription factors of the IIS and select DR pathways, DAF‐1...

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Detalles Bibliográficos
Autores principales: Singh, Anupama, Kumar, Neeraj, Matai, Latika, Jain, Vaibhav, Garg, Amit, Mukhopadhyay, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933660/
https://www.ncbi.nlm.nih.gov/pubmed/27039057
http://dx.doi.org/10.1111/acel.12477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933660/
https://www.ncbi.nlm.nih.gov/pubmed/27039057
http://dx.doi.org/10.1111/acel.12477

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