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Reduced Nrf2 expression mediates the decline in neural stem cell function during a critical middle‐age period

Although it is known that the regenerative function of neural stem/progenitor cells (NSPCs) declines with age, causal mechanisms underlying this phenomenon are not understood. Here, we systematically analyze subventricular zone (SVZ) NSPCs, in various groups of rats across the aging spectrum, using...

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Detalles Bibliográficos
Autores principales: Corenblum, Mandi J., Ray, Sneha, Remley, Quentin W., Long, Min, Harder, Bryan, Zhang, Donna D., Barnes, Carol A., Madhavan, Lalitha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933666/
https://www.ncbi.nlm.nih.gov/pubmed/27095375
http://dx.doi.org/10.1111/acel.12482