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Aging: progressive decline in fitness due to the rising deleteriome adjusted by genetic, environmental, and stochastic processes
Different theories posit that aging is caused by molecular damage, genetic programs, continued development, hyperfunction, antagonistic pleiotropy alleles, mutations, trade‐offs, incomplete repair, etc. Here, I discuss that these ideas can be conceptually unified as they capture particular facets of...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933668/ https://www.ncbi.nlm.nih.gov/pubmed/27060562 http://dx.doi.org/10.1111/acel.12480 |