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Comparative idiosyncrasies in life extension by reduced mTOR signalling and its distinctiveness from dietary restriction
Reduced mechanistic target of rapamycin (mTOR) signalling extends lifespan in yeast, nematodes, fruit flies and mice, highlighting a physiological pathway that could modulate aging in evolutionarily divergent organisms. This signalling system is also hypothesized to play a central role in lifespan e...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933670/ https://www.ncbi.nlm.nih.gov/pubmed/27139919 http://dx.doi.org/10.1111/acel.12489 |