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Characterization of the direct targets of FOXO transcription factors throughout evolution

FOXO transcription factors (FOXOs) are central regulators of lifespan across species, yet they also have cell‐specific functions, including adult stem cell homeostasis and immune function. Direct targets of FOXOs have been identified genome‐wide in several species and cell types. However, whether FO...

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Detalles Bibliográficos
Autores principales: Webb, Ashley E., Kundaje, Anshul, Brunet, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933671/
https://www.ncbi.nlm.nih.gov/pubmed/27061590
http://dx.doi.org/10.1111/acel.12479