Acute systemic DNA damage in youth does not impair immune defense with aging

Aging‐related decline in immunity is believed to be the main driver behind decreased vaccine efficacy and reduced resistance to infections in older adults. Unrepaired DNA damage is known to precipitate cellular senescence, which was hypothesized to be the underlying cause of certain age‐related phen...

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Detalles Bibliográficos
Autores principales: Pugh, Jason L., Foster, Sarah A., Sukhina, Alona S., Petravic, Janka, Uhrlaub, Jennifer L., Padilla‐Torres, Jose, Hayashi, Tomonori, Nakachi, Kei, Smithey, Megan J., Nikolich‐Žugich, Janko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933672/
https://www.ncbi.nlm.nih.gov/pubmed/27072188
http://dx.doi.org/10.1111/acel.12478

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933672/
https://www.ncbi.nlm.nih.gov/pubmed/27072188
http://dx.doi.org/10.1111/acel.12478

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