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Acute systemic DNA damage in youth does not impair immune defense with aging
Aging‐related decline in immunity is believed to be the main driver behind decreased vaccine efficacy and reduced resistance to infections in older adults. Unrepaired DNA damage is known to precipitate cellular senescence, which was hypothesized to be the underlying cause of certain age‐related phen...
Autores principales: | Pugh, Jason L., Foster, Sarah A., Sukhina, Alona S., Petravic, Janka, Uhrlaub, Jennifer L., Padilla‐Torres, Jose, Hayashi, Tomonori, Nakachi, Kei, Smithey, Megan J., Nikolich‐Žugich, Janko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933672/ https://www.ncbi.nlm.nih.gov/pubmed/27072188 http://dx.doi.org/10.1111/acel.12478 |
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