Lipid peroxides as endogenous oxidants forming 8-oxo-guanosine and lipid-soluble antioxidants as suppressing agents

The oxidation of guanosine to 8-oxo-2'-deoxyguanosine (8-oxo-dG) in DNA is closely associated with induction of various diseases, but the endogenous oxidant species involved remains unclear. Hydrogen peroxides (H(2)O(2)) have been considered to be the oxidant, while lipid peroxides are another...

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Detalles Bibliográficos
Autores principales: Kanazawa, Kazuki, Sakamoto, Miku, Kanazawa, Ko, Ishigaki, Yoriko, Aihara, Yoshiko, Hashimoto, Takashi, Mizuno, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933685/
https://www.ncbi.nlm.nih.gov/pubmed/27499574
http://dx.doi.org/10.3164/jcbn.15-122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933685/
https://www.ncbi.nlm.nih.gov/pubmed/27499574
http://dx.doi.org/10.3164/jcbn.15-122

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