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Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice

One of the newest substances, whose antidepressant activity was shown is traxoprodil, which is a selective antagonist of the NR2B subunit of the NMDA receptor. The main goal of the present study was to evaluate the effect of traxoprodil on animals’ behavior using the forced swim test (FST), as well...

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Detalles Bibliográficos
Autores principales: Poleszak, Ewa, Stasiuk, Weronika, Szopa, Aleksandra, Wyska, Elżbieta, Serefko, Anna, Oniszczuk, Anna, Wośko, Sylwia, Świąder, Katarzyna, Wlaź, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933725/
https://www.ncbi.nlm.nih.gov/pubmed/26924124
http://dx.doi.org/10.1007/s11011-016-9810-5