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2-Bromoterguride–a potential atypical antipsychotic drug without metabolic effects in rats

RATIONALE: Recently, we showed that 2-bromoterguride acted as a dopamine D(2) receptor partial agonist, a serotonin 5-HT(2A) and α(2C)-adrenergic receptor antagonist, and exhibited antidopaminergic efficacy in amphetamine-induced locomotion (AIL) in rats without inducing catalepsy. OBJECTIVE: To ext...

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Detalles Bibliográficos
Autores principales: Franke, Robert T., Tarland, Emilia, Fink, Heidrun, Pertz, Heinz H., Brosda, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933731/
https://www.ncbi.nlm.nih.gov/pubmed/27317020
http://dx.doi.org/10.1007/s00213-016-4356-0