Self-assembly of c-myc DNA promoted by a single enantiomer ruthenium complex as a potential nuclear targeting gene carrier

Gene therapy has long been limited in the clinic, due in part to the lack of safety and efficacy of the gene carrier. Herein, a single enantiomer ruthenium(II) complex, Λ-[Ru(bpy)(2)(p-BEPIP)](ClO(4))(2) (Λ-RM0627, bpy = 4,4′-bipyridine, p-BEPIP = 2-(4-phenylacetylenephenyl)imidazole [4,5f][1, 10] p...

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Detalles Bibliográficos
Autores principales: Wu, Qiong, Mei, Wenjie, Zheng, Kangdi, Ding, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933878/
https://www.ncbi.nlm.nih.gov/pubmed/27381008
http://dx.doi.org/10.1038/srep28582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933878/
https://www.ncbi.nlm.nih.gov/pubmed/27381008
http://dx.doi.org/10.1038/srep28582

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