Cargando…
Self-assembly of c-myc DNA promoted by a single enantiomer ruthenium complex as a potential nuclear targeting gene carrier
Gene therapy has long been limited in the clinic, due in part to the lack of safety and efficacy of the gene carrier. Herein, a single enantiomer ruthenium(II) complex, Λ-[Ru(bpy)(2)(p-BEPIP)](ClO(4))(2) (Λ-RM0627, bpy = 4,4′-bipyridine, p-BEPIP = 2-(4-phenylacetylenephenyl)imidazole [4,5f][1, 10] p...
Autores principales: | Wu, Qiong, Mei, Wenjie, Zheng, Kangdi, Ding, Yang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933878/ https://www.ncbi.nlm.nih.gov/pubmed/27381008 http://dx.doi.org/10.1038/srep28582 |
Ejemplares similares
-
Stabilization of MYC G-quadruplex DNA by ruthenium (II) complex overcomes imatinib resistance in chronic myeloid leukemia cells harboring T315I mutation
por: Sun, Yuening, et al.
Publicado: (2022) -
Ruthenium(II) Complexes Coupled by Erianin via a Flexible Carbon Chain as a Potential Stabilizer of c-myc G-Quadruplex DNA
por: Wang, Zhixiang, et al.
Publicado: (2023) -
Chiral ruthenium(ii) complex as potent radiosensitizer of (125)I through DNA-damage-mediated apoptosis
por: Bai, Mingjun, et al.
Publicado: (2018) -
Self-Assembly
of Aromatic Amino Acid Enantiomers into
Supramolecular Materials of High Rigidity
por: Bera, Santu, et al.
Publicado: (2020) -
The substitution of a single amino acid with its enantiomer for control over the adjuvant activity of self-assembling peptides
por: Li, Mingyu, et al.
Publicado: (2020)