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Efficient nucleic acid delivery to murine regulatory T cells by gold nanoparticle conjugates

Immune responses have to be tightly controlled to guarantee maintenance of immunological tolerance and efficient clearance of pathogens and tumorigenic cells without induction of unspecific side effects. CD4(+) CD25(+) regulatory T cells (Tregs) play an important role in these processes due to their...

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Detalles Bibliográficos
Autores principales: Gamrad, Lisa, Rehbock, Christoph, Westendorf, Astrid M., Buer, Jan, Barcikowski, Stephan, Hansen, Wiebke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933883/
https://www.ncbi.nlm.nih.gov/pubmed/27381215
http://dx.doi.org/10.1038/srep28709