Inhibitory effect of 2-methyl-naphtho[1,2,3-de]quinolin-8-one on melanosome transport and skin pigmentation

Melanosomes are lysosome-related organelles with specialized capabilities of melanin synthesis and movement mediated by the Rab27a-Melanophilin-MyosinVa protein complex. In this study, we found that 2-methyl-naphtho[1,2,3-de]quinolin-8-one (MNQO) induced melanosome aggregation around the nucleus in...

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Detalles Bibliográficos
Autores principales: Park, Jong il, Lee, Ha Yeon, Lee, Ji Eun, Myung, Cheol hwan, Hwang, Jae Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933902/
https://www.ncbi.nlm.nih.gov/pubmed/27381646
http://dx.doi.org/10.1038/srep29189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933902/
https://www.ncbi.nlm.nih.gov/pubmed/27381646
http://dx.doi.org/10.1038/srep29189

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