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Antibody-Dependent Enhancement of Dengue Virus Infection in Primary Human Macrophages; Balancing Higher Fusion against Antiviral Responses

The dogma is that the human immune system protects us against pathogens. Yet, several viruses, like dengue virus, antagonize the hosts’ antibodies to enhance their viral load and disease severity; a phenomenon called antibody-dependent enhancement of infection. This study offers novel insights in th...

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Detalles Bibliográficos
Autores principales: Flipse, Jacky, Diosa-Toro, Mayra A., Hoornweg, Tabitha E., van de Pol, Denise P. I., Urcuqui-Inchima, Silvio, Smit, Jolanda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933910/
https://www.ncbi.nlm.nih.gov/pubmed/27380892
http://dx.doi.org/10.1038/srep29201