Mutations in the G-domain of Ski7 cause specific dysfunction in non-stop decay

Ski7 functions as a cofactor in both normal mRNA turnover and non-stop mRNA decay (NSD) mRNA surveillance in budding yeast. The N-terminal region of Ski7 (Ski7(N)) interacts with the ski-complex and the exosome. The C-terminal region of Ski7 (Ski7(C)) binds guanine nucleotides and shares overall seq...

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Detalles Bibliográficos
Autores principales: Horikawa, Wataru, Endo, Kei, Wada, Miki, Ito, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933942/
https://www.ncbi.nlm.nih.gov/pubmed/27381255
http://dx.doi.org/10.1038/srep29295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933942/
https://www.ncbi.nlm.nih.gov/pubmed/27381255
http://dx.doi.org/10.1038/srep29295

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