Dipeptidyl Peptidase-4 Inhibitor Increases Vascular Leakage in Retina through VE-cadherin Phosphorylation

The inhibitors of CD26 (dipeptidyl peptidase-4; DPP4) have been widely prescribed to control glucose level in diabetic patients. DPP4-inhibitors, however, accumulate stromal cell-derived factor-1α (SDF-1α), a well-known inducer of vascular leakage and angiogenesis both of which are fundamental patho...

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Detalles Bibliográficos
Autores principales: Lee, Choon-Soo, Kim, Yun Gi, Cho, Hyun-Jai, Park, Jonghanne, Jeong, Heewon, Lee, Sang-Eun, Lee, Seung-Pyo, Kang, Hyun-Jae, Kim, Hyo-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933943/
https://www.ncbi.nlm.nih.gov/pubmed/27381080
http://dx.doi.org/10.1038/srep29393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933943/
https://www.ncbi.nlm.nih.gov/pubmed/27381080
http://dx.doi.org/10.1038/srep29393

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