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Microbial biotransformation of DON: molecular basis for reduced toxicity

Bacteria are able to de-epoxidize or epimerize deoxynivalenol (DON), a mycotoxin, to deepoxy-deoxynivalenol (deepoxy-DON or DOM-1) or 3-epi-deoxynivalenol (3-epi-DON), respectively. Using different approaches, the intestinal toxicity of 3 molecules was compared and the molecular basis for the reduce...

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Detalles Bibliográficos
Autores principales: Pierron, Alix, Mimoun, Sabria, Murate, Leticia S., Loiseau, Nicolas, Lippi, Yannick, Bracarense, Ana-Paula F. L., Schatzmayr, Gerd, He, Jian Wei, Zhou, Ting, Moll, Wulf-Dieter, Oswald, Isabelle P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4933977/
https://www.ncbi.nlm.nih.gov/pubmed/27381510
http://dx.doi.org/10.1038/srep29105