Single-cell genome-wide bisulfite sequencing uncovers extensive heterogeneity in the mouse liver methylome

BACKGROUND: Transmission fidelity of CpG DNA methylation patterns is not foolproof, with error rates from less than 1 to well over 10 % per CpG site, dependent on preservation of the methylated or unmethylated state and the type of sequence. This suggests a fairly high chance of errors. However, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Gravina, Silvia, Dong, Xiao, Yu, Bo, Vijg, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934005/
https://www.ncbi.nlm.nih.gov/pubmed/27380908
http://dx.doi.org/10.1186/s13059-016-1011-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934005/
https://www.ncbi.nlm.nih.gov/pubmed/27380908
http://dx.doi.org/10.1186/s13059-016-1011-3

Ejemplares similares