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Multi-target siRNA: Therapeutic Strategy for Hepatocellular Carcinoma

Multiple targets RNAi strategy is a preferred way to treat multigenic diseases, especially cancers. In the study, multi-target siRNAs were designed to inhibit NET-1, EMS1 and VEGF genes in hepatocellular carcinoma (HCC) cells. And multi-target siRNAs showed better silencing effects on NET-1, EMS1 an...

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Detalles Bibliográficos
Autores principales: Li, Tiejun, Xue, Yuwen, Wang, Guilan, Gu, Tingting, Li, Yunlong, Zhu, York Yuanyuan, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934040/
https://www.ncbi.nlm.nih.gov/pubmed/27390607
http://dx.doi.org/10.7150/jca.15157