Cargando…

Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma

While primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide, it still does not have a clear mechanism that can explain all clinical cases of the disease. Elevated IOP is associated with increased accumulation of extracellular matrix (ECM) proteins in the trabecular meshwork (T...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhavoronkov, Alex, Izumchenko, Evgeny, Kanherkar, Riya R., Teka, Mahder, Cantor, Charles, Manaye, Kebreten, Sidransky, David, West, Michael D., Makarev, Eugene, Csoka, Antonei Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934076/
https://www.ncbi.nlm.nih.gov/pubmed/27229292
http://dx.doi.org/10.1080/15384101.2016.1170261