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Pro-fibrotic pathway activation in trabecular meshwork and lamina cribrosa is the main driving force of glaucoma
While primary open-angle glaucoma (POAG) is a leading cause of blindness worldwide, it still does not have a clear mechanism that can explain all clinical cases of the disease. Elevated IOP is associated with increased accumulation of extracellular matrix (ECM) proteins in the trabecular meshwork (T...
Autores principales: | Zhavoronkov, Alex, Izumchenko, Evgeny, Kanherkar, Riya R., Teka, Mahder, Cantor, Charles, Manaye, Kebreten, Sidransky, David, West, Michael D., Makarev, Eugene, Csoka, Antonei Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934076/ https://www.ncbi.nlm.nih.gov/pubmed/27229292 http://dx.doi.org/10.1080/15384101.2016.1170261 |
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