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Involvement of nucleophosmin (NPM1/B23) in assembly of infectious HPV16 capsids

We report that during assembly of HPV16 pseudovirus (PsV) the minor capsid protein, L2, interacts with the host nucleolar protein nucleophosmin (NPM1/B23). Exogenously-expressed L2 colocalized with NPM1, a complex containing both proteins, could be immunoprecipitated, and L2 could redirect to the nu...

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Detalles Bibliográficos
Autores principales: Day, Patricia M., Thompson, Cynthia D., Pang, Yuk Ying, Lowy, Douglas R., Schiller, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934132/
https://www.ncbi.nlm.nih.gov/pubmed/27398412
http://dx.doi.org/10.1016/j.pvr.2015.06.005