T-cell activation is enhanced by targeting IL-10 cytokine production in toll-like receptor-stimulated macrophages

Toll-like receptor (TLR) agonists represent potentially useful cancer vaccine adjuvants in their ability to stimulate antigen-presenting cells (APCs) and subsequently amplify the cytotoxic T-cell response. The purpose of this study was to characterize APC responses to TLR activation and to determine...

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Detalles Bibliográficos
Autores principales: Walk, Ryan M, Elliott, Steven T, Blanco, Felix C, Snyder, Jason A, Jacobi, Ashley M, Rose, Scott D, Behlke, Mark A, Salem, Aliasger K, Vukmanovic, Stanislav, Sandler, Anthony D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934151/
https://www.ncbi.nlm.nih.gov/pubmed/27471682
http://dx.doi.org/10.2147/ITT.S32615

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934151/
https://www.ncbi.nlm.nih.gov/pubmed/27471682
http://dx.doi.org/10.2147/ITT.S32615

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