DOCLASP - Docking ligands to target proteins using spatial and electrostatic congruence extracted from a known holoenzyme and applying simple geometrical transformations

The ability to accurately and effectively predict the interaction between proteins and small drug-like compounds has long intrigued researchers for pedagogic, humanitarian and economic reasons. Protein docking methods (AutoDock, GOLD, DOCK, FlexX and Glide to name a few) rank a large number of possi...

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Detalles Bibliográficos
Autor principal: Chakraborty, Sandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2016
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934513/
https://www.ncbi.nlm.nih.gov/pubmed/27429737
http://dx.doi.org/10.12688/f1000research.5145.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934513/
https://www.ncbi.nlm.nih.gov/pubmed/27429737
http://dx.doi.org/10.12688/f1000research.5145.3

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