Constitutively active form of natriuretic peptide receptor 2 ameliorates experimental pulmonary arterial hypertension

We recently found a constitutively active mutant of natriuretic peptide receptor 2 (caNPR2; V883M), which synthesizes larger amounts of cyclic guanosine monophosphate (cGMP) intracellularly without any ligand stimulation than existing drugs. The aim of this study was to investigate the therapeutic e...

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Detalles Bibliográficos
Autores principales: Nawa, Nobutoshi, Ishida, Hidekazu, Katsuragi, Shinichi, Baden, Hiroki, Takahashi, Kunihiko, Higeno, Ryota, Torigoe, Fumiko, Mihara, Seiko, Narita, Jun, Miura, Kohji, Nakamura, Kazufumi, Kogaki, Shigetoyo, Ozono, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934588/
https://www.ncbi.nlm.nih.gov/pubmed/27419193
http://dx.doi.org/10.1038/mtm.2016.44

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934588/
https://www.ncbi.nlm.nih.gov/pubmed/27419193
http://dx.doi.org/10.1038/mtm.2016.44

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