Identification of neutral tumor evolution across cancer types

Despite extraordinary efforts to profile cancer genomes, interpreting the vast amount of genomic data in the light of cancer evolution remains challenging. Here we demonstrate that neutral tumor evolution results in a power-law distribution of the mutant allele frequencies reported by next-generatio...

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Detalles Bibliográficos
Autores principales: Williams, Marc J, Werner, Benjamin, Barnes, Chris P, Graham, Trevor A, Sottoriva, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934603/
https://www.ncbi.nlm.nih.gov/pubmed/26780609
http://dx.doi.org/10.1038/ng.3489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934603/
https://www.ncbi.nlm.nih.gov/pubmed/26780609
http://dx.doi.org/10.1038/ng.3489

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