Llwytho...

Identification of neutral tumor evolution across cancer types

Despite extraordinary efforts to profile cancer genomes, interpreting the vast amount of genomic data in the light of cancer evolution remains challenging. Here we demonstrate that neutral tumor evolution results in a power-law distribution of the mutant allele frequencies reported by next-generatio...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Williams, Marc J, Werner, Benjamin, Barnes, Chris P, Graham, Trevor A, Sottoriva, Andrea
Fformat: Online Erthygl Texto
Iaith:English
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934603/
https://www.ncbi.nlm.nih.gov/pubmed/26780609
http://dx.doi.org/10.1038/ng.3489