Wird geladen …

Identification of neutral tumor evolution across cancer types

Despite extraordinary efforts to profile cancer genomes, interpreting the vast amount of genomic data in the light of cancer evolution remains challenging. Here we demonstrate that neutral tumor evolution results in a power-law distribution of the mutant allele frequencies reported by next-generatio...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Williams, Marc J, Werner, Benjamin, Barnes, Chris P, Graham, Trevor A, Sottoriva, Andrea
Format: Online Artikel Text
Sprache:English
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934603/
https://www.ncbi.nlm.nih.gov/pubmed/26780609
http://dx.doi.org/10.1038/ng.3489