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Identification of neutral tumor evolution across cancer types

Despite extraordinary efforts to profile cancer genomes, interpreting the vast amount of genomic data in the light of cancer evolution remains challenging. Here we demonstrate that neutral tumor evolution results in a power-law distribution of the mutant allele frequencies reported by next-generatio...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Williams, Marc J, Werner, Benjamin, Barnes, Chris P, Graham, Trevor A, Sottoriva, Andrea
स्वरूप: Online लेख मूलपाठ
भाषा:English
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934603/
https://www.ncbi.nlm.nih.gov/pubmed/26780609
http://dx.doi.org/10.1038/ng.3489