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Identification of neutral tumor evolution across cancer types

Despite extraordinary efforts to profile cancer genomes, interpreting the vast amount of genomic data in the light of cancer evolution remains challenging. Here we demonstrate that neutral tumor evolution results in a power-law distribution of the mutant allele frequencies reported by next-generatio...

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Bibliografische gegevens
Hoofdauteurs: Williams, Marc J, Werner, Benjamin, Barnes, Chris P, Graham, Trevor A, Sottoriva, Andrea
Formaat: Online Artikel Texto
Taal:English
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4934603/
https://www.ncbi.nlm.nih.gov/pubmed/26780609
http://dx.doi.org/10.1038/ng.3489